Mental Health Education and News

Nathan E Botts
/ Categories: Mental Health

Treatment Targets, Target Engagement, And Target Populations in Mental Health Services Research

Treatment Targets, Target Engagement, And Target Populations in Mental Health Services ResearchClinical trial research can garner compelling evidence of an intervention’s effect. Design considerations like prospective assignment, choice of comparison group(s), blinding, generalizability of sample, sampling frame, and the setting where the trial is conducted, all help determine whether the primary research question is about efficacy (could the intervention work under ideal situations) or effectiveness (does it work in under real-world constraints). However, these considerations do not necessarily provide insights into why an intervention works--or does not work. This webinar started with a brief overview of the experimental therapeutics paradigm, which provides a framework to understand targets and mechanisms of action for all NIMH-funded clinical trial research, including mental health services research. Following the overview, two high priority NIMH-funded research studies in the context of the experimental therapeutic paradigm were presented: 1) Family Groups for Urban Youth with Disruptive Behavior (R01) and 2) African Regional Research Partnerships for Scaling Up Child Mental Health EBPs (U19). The webinar concluded with a facilitated discussion and presentation of funding opportunities and NIMH-sponsored events focused on experimental therapeutics. This webinar was moderated by Dr. Makeda Williams, Health Scientist Administrator in NIMH’s Office for Research on Disparities and Global Mental Health.

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