Nathan E Botts / Wednesday, January 4, 2017 / Categories: Mental Health PMDD Linked to Gene Network PMDD Linked to Gene NetworkNational Institutes of Health (NIH) researchers have discovered molecular mechanisms that may underlie a woman’s susceptibility to disabling irritability, sadness, and anxiety in the days leading up to her menstrual period. Such premenstrual dysphoric disorder (PMDD) affects 2 to 5 percent of women of reproductive age, whereas less severe premenstrual syndrome (PMS) is much more common. “We found dysregulated expression in a suspect gene complex which adds to evidence that PMDD is a disorder of cellular response to estrogen and progesterone,” explained Peter Schmidt, M.D. of the NIH’s National Institute of Mental Health, Behavioral Endocrinology Branch. “Learning more about the role of this gene complex holds hope for improved treatment of such prevalent reproductive endocrine-related mood disorders.” For more information see press release: Sex Hormone–Sensitive Gene Complex Linked to Premenstrual Mood Disorder https://www.nimh.nih.gov/news/science-news/2017/sex-hormone-sensitive-gene-complex-linked-to-premenstrual-mood-disorder.shtmlLink to original article Previous Article Making New Year's Resolutions That Last Next Article Men and Depression: Patrick McCathern, First Sergeant, U.S. Air Force, Retired Print 246 Rate this article: No rating 0Upvote 0Downvote Leave a comment Name: Please enter a name. Email: Please enter an email address. Please enter a valid email address. Comment: Please enter comment. Add comment