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DeFronzo on a novel renal-hepatic axis in endogenous glucose production, arguments for and agains...

DeFronzo on a novel renal-hepatic axis in endogenous glucose production, arguments for and agains...Welcome to the June 2024 episode of DiabetesBio—the American Diabetes Association’s podcast for its flagship research publication, Diabetes (https://diabetesjournals.org/diabetes) . In this episode of DiabetesBio, Drs. Kirk Habegger, Darleen Sandoval, and Kevin Williams discuss the latest and greatest content in the June 2024 issue of Diabetes.  2:27: Darleen and Kirk are joined by Dr. Ralph A. DeFronzo (https://directory.uthscsa.edu/academics/profile/defronzo) , senior author of the article “Effect of Dapagliflozin on Renal and Hepatic Glucose Kinetics in T2D and NGT Subjects.” This article is freely accessible at https://doi.org/10.2337/db23-0457. 20:26: In this month’s Sweet Talk segment, Kevin and Kirk highlight this month’s Point-Counterpoint feature on whether a new model is needed on the regulation of β-cell KATP channels in glucose metabolism. First, they talk to Drs. Matthew J. Merrins (https://bmolchem.wisc.edu/staff/merrins-matthew/) and Richard G. Kibbey (https://medicine.yale.edu/profile/richard-kibbey/) , authors of the Counterpoint, titled “Glucose Regulation of β-Cell KATP Channels: It Is Time for a New Model!” This article is freely accessible at https://doi.org/10.2337/dbi23-0032.  35:00: Kevin next is joined by Drs. Guy A. Rutter (https://profiles.imperial.ac.uk/g.rutter) and Ian R. Sweet (https://uwmdi.org/faculty/ian-sweet-phd/) , authors of the Point article, titled “Glucose Regulation of β-Cell KATP Channels: Is a New Model Needed?” This article is freely accessible at https://doi.org/10.2337/dbi23-0031.    To learn more about Diabetes and DiabetesBio, please visit diabetesjournals.org/diabetes (https://diabetesjournals.org/diabetes) . Thank you for listening, and don’t forget to smash that “follow” button!

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